Laptm4a | lysosomal-associated protein transmembrane 4A
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Limbs/digits/tail Nervous system Vision/eye Skeleton Cardiovascular system
13 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased fasting circulating glucose level | 1 supporting dataset | Laptm4atm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.81x10-11 | ||
| short tibia | 1 supporting dataset | Laptm4atm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.53x10-7 | ||
| prolonged ST segment | 1 supporting dataset | Laptm4atm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.37x10-6 | ||
| increased prepulse inhibition | 1 supporting dataset | Laptm4atm1b(EUCOMM)Hmgu | homozygote | Early adult | 8.84x10-5 | ||
| decreased total retina thickness | 1 supporting dataset | Laptm4atm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.4x10-6 |
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External links
No external links available for Laptm4a.
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| Laptm4atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Laptm4atm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Laptm4atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |
| Laptm4atm79747(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |