Igfals | insulin-like growth factor binding protein, acid labile subunit

GeneMGI:107973Synonyms: Albs, ALS

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes



increased circulating cholesterol level	1 supporting dataset	Igfals^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.04x10^-5
abnormal cholesterol homeostasis	1 supporting dataset	Igfals^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.76x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Igfals.

Associated images

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Histopathology

There is no histopathology data found for Igfals.

IMPC related publications

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External links

No external links available for Igfals.

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*Igfals^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Igfals^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Igfals^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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