Lrig1 | leucine-rich repeats and immunoglobulin-like domains 1

GeneMGI:107935Synonyms: LIG-1, Img

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Integument Growth/size/body region Limbs/digits/tail Behavior/neurological Cardiovascular system

15 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

abnormal tail morphology1 supporting datasetLrig1tm1a(EUCOMM)WtsihomozygoteEarly adult2.21x10-6 
increased heart weight1 supporting datasetLrig1tm1a(EUCOMM)WtsihomozygoteEarly adult1.1x10-8 
abnormal behavior1 supporting datasetLrig1tm1a(EUCOMM)WtsihomozygoteEarly adult4.99x10-5 
abnormal skin condition1 supporting datasetLrig1tm1a(EUCOMM)WtsihomozygoteEarly adult1.34x10-11 
decreased body weight5 supporting datasetsLrig1tm1a(EUCOMM)WtsihomozygoteEarly adult1.01x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lrig1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Lrig1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lrig1tm42916(L1L2_gt2_Del_LacZ)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Lrig1tm42916(pL1L2_frt15_BetactinBSD_frt14_neo_Rox)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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