Zfp462 | zinc finger protein 462

GeneMGI:107690Synonyms: Zfpip, Gt4-2, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Embryo Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Zfp462^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased lean body mass	2 supporting datasets	Zfp462^em1(IMPC)Tcp	heterozygote	Early adult	1.14x10^-10
thrombocytopenia	1 supporting dataset	Zfp462^em1(IMPC)Tcp	heterozygote	Early adult	5.71x10^-8
edema	1 supporting dataset	Zfp462^em1(IMPC)Tcp	homozygote	E15.5	N/A ^*
increased startle reflex	1 supporting dataset	Zfp462^em1(IMPC)Tcp	heterozygote	Early adult	1.24x10^-7
increased total body fat amount	2 supporting datasets	Zfp462^em1(IMPC)Tcp	heterozygote	Early adult	2.34x10^-7
impaired glucose tolerance	1 supporting dataset	Zfp462^em1(IMPC)Tcp	heterozygote	Early adult	3.4x10^-5
abnormal embryo size	1 supporting dataset	Zfp462^em1(IMPC)Tcp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zfp462.

Associated images

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Histopathology

There is no histopathology data found for Zfp462.

IMPC related publications

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External links

No external links available for Zfp462.

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*Zfp462^em1(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Zfp462^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Zfp462^{tm459785(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Zfp462^{tm459827(L1L2_GT2_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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