Prdm2 | PR domain containing 2, with ZNF domain

GeneMGI:107628Synonyms: Riz, Riz1, +4 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased basophil cell number2 supporting datasetsPrdm2em1(IMPC)MarchomozygoteEarly adult2.95x10-16 
increased circulating creatinine level1 supporting datasetPrdm2em1(IMPC)MarchomozygoteEarly adult3.18x10-6 
increased eosinophil cell number2 supporting datasetsPrdm2em1(IMPC)MarchomozygoteEarly adult1.29x10-15 
increased mean corpuscular hemoglobin1 supporting datasetPrdm2em1(IMPC)MarchomozygoteEarly adult1.77x10-14 
increased mean corpuscular hemoglobin concentration1 supporting datasetPrdm2em1(IMPC)MarchomozygoteEarly adult1.35x10-34 
decreased hematocrit1 supporting datasetPrdm2em1(IMPC)MarchomozygoteEarly adult7.88x10-5 
increased grip strength1 supporting datasetPrdm2em1(IMPC)MarchomozygoteEarly adult5.31x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prdm2em1(IMPC)MarcDeletionmouse
Prdm2tm249368(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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