Ube2e1 | ubiquitin-conjugating enzyme E2E 1

GeneMGI:107411Synonyms: Ubce5, ubcM2, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Vision/eye Hematopoietic system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean platelet volume1 supporting datasetUbe2e1em1(IMPC)MarchomozygoteEarly adult2.23x10-5 
increased hematocrit1 supporting datasetUbe2e1em1(IMPC)MarchomozygoteEarly adult1.59x10-14 
increased mean corpuscular volume1 supporting datasetUbe2e1em1(IMPC)MarchomozygoteEarly adult5.75x10-35 
increased monocyte cell number1 supporting datasetUbe2e1em1(IMPC)MarchomozygoteEarly adult5.42x10-8 
decreased mean corpuscular hemoglobin concentration1 supporting datasetUbe2e1em1(IMPC)MarchomozygoteEarly adult4.88x10-35 
abnormal retina morphology1 supporting datasetUbe2e1em1(IMPC)MarchomozygoteEarly adult2.47x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ube2e1em1(IMPC)MarcDeletionmouse
Ube2e1tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ube2e1tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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