Ing4 | inhibitor of growth family, member 4

GeneMGI:107307Synonyms: D6Wsu147e, D6Xrf92, +1 more

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Limbs/digits/tail Hematopoietic system Skeleton Renal/urinary system

11 No significant impact

6 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating chloride level1 supporting datasetIng4em1(IMPC)TcphomozygoteEarly adult1.51x10-5 
decreased circulating alkaline phosphatase level1 supporting datasetIng4em1(IMPC)TcphomozygoteEarly adult2.09x10-5 
small kidney1 supporting datasetIng4em1(IMPC)TcphomozygoteEarly adultN/A * 
increased circulating sodium level1 supporting datasetIng4em1(IMPC)TcphomozygoteEarly adult2.67x10-5 
decreased lymphocyte cell number1 supporting datasetIng4em1(IMPC)TcphomozygoteEarly adult9.91x10-5 
increased neutrophil cell number1 supporting datasetIng4em1(IMPC)TcphomozygoteEarly adult5.32x10-5 
short tibia1 supporting datasetIng4em1(IMPC)TcphomozygoteEarly adult5.12x10-8 
abnormal skin morphology1 supporting datasetIng4em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ing4em1(IMPC)TcpExon Deletionmouse

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