Rbfox3 | RNA binding protein, fox-1 homolog (C. elegans) 3
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological
17 No significant impact
5 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased grip strength | 2 supporting datasets | Rbfox3tm1a(EUCOMM)Hmgu | homozygote | Early adult | 5.11x10-6 | ||
| increased startle reflex | 4 supporting datasets | Rbfox3tm1a(EUCOMM)Hmgu | homozygote | Early adult | 2.49x10-5 | ||
| decreased circulating alkaline phosphatase level | 1 supporting dataset | Rbfox3tm1a(EUCOMM)Hmgu | homozygote | Early adult | 2.23x10-7 | ||
| abnormal tail movements | 1 supporting dataset | Rbfox3tm1a(EUCOMM)Hmgu | homozygote | Early adult | 1.01x10-5 | ||
| abnormal response to new environment | 1 supporting dataset | Rbfox3tm1a(EUCOMM)Hmgu | homozygote | Early adult | 2.06x10-5 |
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Human diseases caused by Rbfox3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Rbfox3.
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