Cox8a | cytochrome c oxidase subunit 8A

GeneMGI:105959Synonyms: COX8L, COX VIII-L

Physiological systems

11 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

8 No significant impact

13 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength2 supporting datasetsCox8aem1(IMPC)MarchomozygoteEarly adult1.47x10-8 
decreased circulating phosphate level1 supporting datasetCox8aem1(IMPC)MarchomozygoteEarly adult4.5x10-5 
decreased locomotor activity1 supporting datasetCox8aem1(IMPC)MarchomozygoteEarly adult3.13x10-5 
increased circulating triglyceride level1 supporting datasetCox8aem1(IMPC)MarchomozygoteEarly adult1.69x10-11 
abnormal retina morphology1 supporting datasetCox8aem1(IMPC)MarchomozygoteEarly adult5.37x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Cox8aem1(IMPC)MarcDeletionmouse
Cox8atm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cox8atm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter