Hsd17b4 | hydroxysteroid (17-beta) dehydrogenase 4

GeneMGI:105089Synonyms: D-bifunctional protein, Mfp-2, +5 more

Physiological systems

21 / 24 physiological systems tested

15 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hearing/vestibular/ear Hematopoietic system Craniofacial Cardiovascular system Renal/urinary system Homeostasis/metabolism Embryo Vision/eye Behavior/neurological Skeleton Mortality/aging

6 No significant impact

3 Not tested

Gene metrics:24Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Human diseases caused by Hsd17b4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

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IMPC related publications

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Order Mouse and ES Cells

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