Satb1 | special AT-rich sequence binding protein 1

GeneMGI:105084Synonyms: 2610306G12Rik

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Hearing/vestibular/ear Vision/eye Behavior/neurological Skeleton Mortality/aging

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

3Associated diseases

Expression examined in:48Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



hyperactivity	4 supporting datasets	Satb1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.66x10^-5
increased bone mineral content	1 supporting dataset	Satb1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.63x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Satb1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Satb1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	Satb1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.28x10^-5
abnormal bone structure	1 supporting dataset	Satb1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	9.81x10^-5
abnormal auditory brainstem response	1 supporting dataset	Satb1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.6x10^-5
increased exploration in new environment	1 supporting dataset	Satb1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.34x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Satb1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Satb1.

Associated images

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Histopathology

There is no histopathology data found for Satb1.

IMPC related publications

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External links

No external links available for Satb1.

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*Satb1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Satb1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Satb1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Satb1^{tm83411(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Satb1^{tm83411(L1L2_gt1_Del_LacZ)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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