Satb1 | special AT-rich sequence binding protein 1
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Hearing/vestibular/ear Vision/eye Behavior/neurological Skeleton Mortality/aging
14 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
3Associated diseases
Expression examined in:48Adult tissues
0Embryo tissues
| hyperactivity | 4 supporting datasets | Satb1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.66x10-5 | ||
| increased bone mineral content | 1 supporting dataset | Satb1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 8.63x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Satb1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal vitreous body morphology | 1 supporting dataset | Satb1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1x10-6 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Satb1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.28x10-5 | ||
| abnormal bone structure | 1 supporting dataset | Satb1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 9.81x10-5 | ||
| abnormal auditory brainstem response | 1 supporting dataset | Satb1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.6x10-5 | ||
| increased exploration in new environment | 1 supporting dataset | Satb1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.34x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Satb1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
| | | | | | | | | | |
| adrenal gland | heterozygote | Section images | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | Section images | 100% (2/2) | 0.19% (1/533) |
| brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | Section images | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
| cerebellum | heterozygote | Section images | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | Section images | 100% (2/2) | 0.41% (2/491) |
| epididymis | heterozygote | Section images | 100% (1/1) | 87.5% (21/24) |
| esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
External links
No external links available for Satb1.
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| Satb1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Satb1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Satb1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Satb1tm83411(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Satb1tm83411(L1L2_gt1_Del_LacZ) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |