Gpx1 | glutathione peroxidase 1

GeneMGI:104887Synonyms: GSHPx-1, CGPx, +3 more

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Growth/size/body region

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small testis	1 supporting dataset	Gpx1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Gpx1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Gpx1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Gpx1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Gpx1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.27x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression



adrenal gland	heterozygote	Section images	100% (2/2)	0.7% (4/570)
aorta	heterozygote	Section images	100% (2/2)	0.19% (1/533)
blood	heterozygote	Section images	100% (2/2)	0% (0/17)
bone marrow	heterozygote	Section images	100% (2/2)	0% (0/22)
brain	heterozygote	n/a	100% (2/2)	0.86% (5/579)
brainstem	heterozygote	n/a	n/a	0.41% (2/490)
brown adipose tissue	heterozygote	Section images	100% (2/2)	0% (0/588)
cartilage tissue	heterozygote	n/a	n/a	0.22% (1/454)
cecum	heterozygote	Section images	100% (2/2)	7.75% (22/284)
cerebellum	heterozygote	Section images	100% (2/2)	0.56% (3/532)

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Associated images

203 images

Adult LacZ

LacZ Images Section

10 images

X-ray

XRay Images Forepaw

10 images

X-ray

XRay Images Hind Leg and Hip

10 images

X-ray

XRay Images Skull Dorso Ventral Orientation

10 images

X-ray

XRay Images Skull Lateral Orientation

10 images

X-ray

XRay Images Whole Body Dorso Ventral

10 images

X-ray

XRay Images Whole Body Lateral Orientation

Histopathology

There is no histopathology data found for Gpx1.

IMPC related publications

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External links

No external links available for Gpx1.

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*Gpx1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Gpx1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Gpx1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

My Genes

Gpx1 | glutathione peroxidase 1

Physiological systems

3 Significantly impacted by the knock-out

18 No significant impact

3 Not tested

Data collections

Phenotypes

lacZ Expression

Associated images

Adult LacZ

X-ray

X-ray

X-ray

X-ray

X-ray

X-ray

Histopathology

IMPC related publications

External links

Order Mouse and ES Cells

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Access Data Release 22.1 Data