Ppp1cb | protein phosphatase 1 catalytic subunit beta

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased exploration in new environment1 supporting datasetPpp1cbem2(IMPC)MarcheterozygoteEarly adult1.82x10-7 
preweaning lethality, complete penetrance1 supporting datasetPpp1cbem2(IMPC)MarchomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ppp1cbem2(IMPC)MarcDeletionmouse
Ppp1cbtm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

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