Lta | lymphotoxin A
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Respiratory system Hematopoietic system
16 No significant impact
3 Not tested
Data collections
Gene metrics:8Significant phenotypes
3Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| increased bronchoconstrictive response | 1 supporting dataset | Ltatm1.1(KOMP)Vlcg | homozygote | Early adult | 8.65x10-5 | ||
| increased leukocyte cell number | 1 supporting dataset | Ltatm1.1(KOMP)Vlcg | homozygote | Early adult | 5.69x10-33 | ||
| decreased monocyte cell number | 1 supporting dataset | Ltatm1.1(KOMP)Vlcg | homozygote | Early adult | 4.08x10-6 | ||
| increased neutrophil cell number | 1 supporting dataset | Ltatm1.1(KOMP)Vlcg | homozygote | Early adult | 3.19x10-16 | ||
| increased eosinophil cell number | 1 supporting dataset | Ltatm1.1(KOMP)Vlcg | homozygote | Early adult | 5.45x10-5 | ||
| decreased body length | 1 supporting dataset | Ltatm1.1(KOMP)Vlcg | homozygote | Early adult | 5.52x10-6 | ||
| increased lymphocyte cell number | 1 supporting dataset | Ltatm1.1(KOMP)Vlcg | homozygote | Early adult | 2.48x10-31 | ||
| increased pulmonary ventilation | 1 supporting dataset | Ltatm1.1(KOMP)Vlcg | homozygote | Early adult | 6.86x10-5 |
| | | | | | | | | | |
External links
No external links available for Lta.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Ltatm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Ltatm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Ltatm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |