Fkbp10 | FK506 binding protein 10
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Nervous system Behavior/neurological Skeleton Mortality/aging
16 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased startle reflex | 7 supporting datasets | Fkbp10tm2a(EUCOMM)Wtsi | heterozygote | Early adult | 4.13x10-15 | ||
| abnormal bone mineralization | 1 supporting dataset | Fkbp10tm2a(EUCOMM)Wtsi | heterozygote | Early adult | 9.86x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Fkbp10tm2a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal tail movements | 1 supporting dataset | Fkbp10tm2a(EUCOMM)Wtsi | heterozygote | Early adult | 8.33x10-5 | ||
| decreased prepulse inhibition | 1 supporting dataset | Fkbp10tm2a(EUCOMM)Wtsi | heterozygote | Early adult | 6.67x10-5 |
| | | | | | | | | | |
External links
No external links available for Fkbp10.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Fkbp10tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Fkbp10tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Fkbp10tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |