Fkbp10 | FK506 binding protein 10

GeneMGI:104769Synonyms: 65kDa, Fkbp6, +3 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Nervous system Behavior/neurological Skeleton Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex7 supporting datasetsFkbp10tm2a(EUCOMM)WtsiheterozygoteEarly adult4.13x10-15 
abnormal bone mineralization1 supporting datasetFkbp10tm2a(EUCOMM)WtsiheterozygoteEarly adult9.86x10-5 
preweaning lethality, complete penetrance1 supporting datasetFkbp10tm2a(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal tail movements1 supporting datasetFkbp10tm2a(EUCOMM)WtsiheterozygoteEarly adult8.33x10-5 
decreased prepulse inhibition1 supporting datasetFkbp10tm2a(EUCOMM)WtsiheterozygoteEarly adult6.67x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Fkbp10tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Fkbp10tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Fkbp10tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter