Fkbp10 | FK506 binding protein 10
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Nervous system Behavior/neurological Skeleton Mortality/aging
16 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased startle reflex | 7 supporting datasets | Fkbp10tm2a(EUCOMM)Wtsi | heterozygote | Early adult | 4.13x10-15 | ||
| abnormal bone mineralization | 1 supporting dataset | Fkbp10tm2a(EUCOMM)Wtsi | heterozygote | Early adult | 9.86x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Fkbp10tm2a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal tail movements | 1 supporting dataset | Fkbp10tm2a(EUCOMM)Wtsi | heterozygote | Early adult | 8.33x10-5 | ||
| decreased prepulse inhibition | 1 supporting dataset | Fkbp10tm2a(EUCOMM)Wtsi | heterozygote | Early adult | 6.67x10-5 |
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Human diseases caused by Fkbp10 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Fkbp10.
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| Fkbp10tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Fkbp10tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Fkbp10tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |