Reln | reelin
GeneMGI:103022
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Reproductive system Immune system Integument Behavior/neurological Mortality/aging
17 No significant impact
2 Not tested
Data collections
Gene metrics:7Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| no spontaneous movement | 1 supporting dataset | Relnem1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Relnem1(IMPC)Mbp | heterozygote | E18.5 | N/A * | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Relnem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| male infertility | 1 supporting dataset | Relnem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| female infertility | 1 supporting dataset | Relnem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Relnem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal lymph node morphology | 1 supporting dataset | Relnem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Relnem1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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Human diseases caused by Reln mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Reln.
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| Relnem1(IMPC)Mbp | Exon Deletion | | mouse |
| Relntm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Relntm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Relntm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |
| Relntm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |