Foxn1 | forkhead box N1

GeneMGI:102949Synonyms: Hfh11, whn, +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Integument Endocrine/exocrine gland Hematopoietic system Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

3Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Foxn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	2 supporting datasets	Foxn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal skin morphology	2 supporting datasets	Foxn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
athymia	2 supporting datasets	Foxn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Foxn1.

Associated images

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Histopathology

There is no histopathology data found for Foxn1.

IMPC related publications

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External links

No external links available for Foxn1.

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*Foxn1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Foxn1^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Foxn1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Foxn1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Foxn1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Foxn1^{tm8(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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