Fgl1 | fibrinogen-like protein 1

GeneMGI:102795

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal bone structure	1 supporting dataset	Fgl1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.95x10^-7
increased circulating HDL cholesterol level	1 supporting dataset	Fgl1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	6.81x10^-7
increased circulating glucose level	1 supporting dataset	Fgl1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.3x10^-5
increased circulating cholesterol level	1 supporting dataset	Fgl1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.64x10^-5
increased total body fat amount	1 supporting dataset	Fgl1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	6.43x10^-5
increased lean body mass	1 supporting dataset	Fgl1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.69x10^-5
abnormal bone mineralization	1 supporting dataset	Fgl1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.41x10^-9
increased bone mineral content	1 supporting dataset	Fgl1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.97x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fgl1.

Associated images

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Histopathology

There is no histopathology data found for Fgl1.

IMPC related publications

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External links

No external links available for Fgl1.

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*Fgl1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Fgl1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Fgl1^{tm84212(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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