Fstl1 | follistatin-like 1
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system
16 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| increased circulating cholesterol level | 1 supporting dataset | Fstl1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.67x10-5 | ||
| increased lymphocyte cell number | 1 supporting dataset | Fstl1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.05x10-5 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Fstl1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.44x10-5 | ||
| decreased neutrophil cell number | 1 supporting dataset | Fstl1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.16x10-5 | ||
| impaired glucose tolerance | 1 supporting dataset | Fstl1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.63x10-5 | ||
| increased circulating HDL cholesterol level | 1 supporting dataset | Fstl1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.06x10-5 |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 100% (2/2) | 0.19% (1/533) |
| bone | heterozygote | n/a | 100% (2/2) | 0% (0/394) |
| brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 100% (2/2) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 100% (2/2) | 0.41% (2/491) |
| esophagus | heterozygote | n/a | 100% (2/2) | 1.67% (7/419) |
External links
No external links available for Fstl1.
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| Fstl1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Fstl1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Fstl1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Fstl1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |