Rab18 | RAB18, member RAS oncogene family

GeneMGI:102790

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



impaired pupillary reflex	1 supporting dataset	Rab18^{Gt(EUCE0233a03)Hmgu}	heterozygote	Early adult	7.94x10^-6
limb grasping	1 supporting dataset	Rab18^{Gt(EUCE0233a03)Hmgu}	heterozygote	Early adult	3.55x10^-7
decreased circulating creatinine level	1 supporting dataset	Rab18^{Gt(EUCE0233a03)Hmgu}	heterozygote	Early adult	3.36x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rab18.

Associated images

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Histopathology

There is no histopathology data found for Rab18.

IMPC related publications

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External links

No external links available for Rab18.

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*Rab18^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Rab18^{tm80910(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Rab18^{tm80910(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes