Aimp1 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Embryo Growth/size/body region Hematopoietic system Mortality/aging
13 No significant impact
4 Not tested
Data collections
Gene metrics:10Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Aimp1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Aimp1em1(IMPC)Tcp | homozygote | E18.5 | N/A * | ||
| absent seminal vesicle | 1 supporting dataset | Aimp1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| hydrometra | 1 supporting dataset | Aimp1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| enlarged spleen | 2 supporting datasets | Aimp1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| male infertility | 1 supporting dataset | Aimp1em1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Aimp1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Aimp1.
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| Aimp1em1(IMPC)Tcp | Exon Deletion | | mouse |
| Aimp1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Aimp1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Aimp1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Aimp1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Aimp1tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Aimp1tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |