Cdc27 | cell division cycle 27

GeneMGI:102685Synonyms: APC3

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	1 supporting dataset	Cdc27^tm1dIcs	heterozygote	Early adult	9.21x10^-5
increased total body fat amount	1 supporting dataset	Cdc27^tm1dIcs	heterozygote	Early adult	4.12x10^-5
decreased exploration in new environment	1 supporting dataset	Cdc27^tm1dIcs	heterozygote	Early adult	1.7x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cdc27.

Associated images

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Histopathology

There is no histopathology data found for Cdc27.

IMPC related publications

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External links

No external links available for Cdc27.

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*Cdc27^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cdc27^tm1aIcs*	KO first allele (reporter-tagged insertion with conditional potential)	‌	ES Cell mouse
*Cdc27^tm1dIcs*	Deletion allele (post-Flp and Cre with no reporter)	‌	mouse
*Cdc27^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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