Ccl8 | C-C motif chemokine ligand 8
Physiological systems
21 / 24 physiological systems tested
21 No significant impact
3 Not tested
Data collections
Gene metrics:0Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| adrenal gland | heterozygote | n/a | 0% (0/4) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/4) | 0.19% (1/533) |
| blood | heterozygote | n/a | 0% (0/2) | 0% (0/17) |
| bone marrow | heterozygote | n/a | 0% (0/2) | 0% (0/22) |
| brain | heterozygote | n/a | 0% (0/4) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/4) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | n/a | 0.22% (1/454) |
| cecum | heterozygote | n/a | 50% (2/4) | 7.75% (22/284) |
| cerebellum | heterozygote | n/a | 0% (0/4) | 0.56% (3/532) |
Human diseases caused by Ccl8 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Ccl8.
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| Ccl8tm115800(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Ccl8tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ccl8tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ccl8tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |